Principal Investigator: Dr Benjamin Turney
Department: Nuffield Department of Surgical Sciences
Institution: University of OxfordTags: 885, diet, kidney, stone, urolithiasis
1a: Kidney stone disease affects around 10% of the population at some point in their lifetime. In the last 10 years there has been a significant increase (67%) in the number of hospital diagnoses relating to stone disease (HES data). There is relatively limited data on causation. It is thought that diet and lifestyle have a significant impact on risk.
The aim of this project is to identify stone-forming patients in the UK Biobank using the HES link (6589 incident cases as of 16/9/14) and investigate potential dietary and lifestyle risk factors.
1b: This study would provide information for kidney stone formers to reduce their risk of recurrent stone formation. As such it meets one of the UK Biobank’s objectives: to improve prevention of disease.
1c: Stone forming patients will be identified using ICD codes and/or OPCS codes. Analysis of lifestyle and dietary factors will be compared with non-stone formers in the cohort.
1d: A subset of patients with stones will be identified but their lifestyle and dietary data will need to be compared to the entire cohort.