Last updated:
ID:
74395
Start date:
16 June 2021
Project status:
Current
Principal investigator:
Pim van der Harst
Lead institution:
University Medical Center Groningen, Netherlands

Cardiovascular diseases are responsible for a major part of the morbidity and mortality worldwide. Major cardiovascular diseases include coronary artery disease, atrial fibrillation, heart failure, and hypertension. Over the past decades, our understanding of the mechanisms leading to the development of these diseases has improved, as well as the therapeutic options. Large population-based study like the UK Biobank with over 500.000 individuals has opened up new possibilities to further our understanding of disease mechanisms as well as progression, which would eventually help us improve the strategies combatting these diseases.
In this project we will incorporate artificial intelligence alongside with conventional methods in the analysis of the UK Biobank data with the objectives to 1) identify new risk factors related to cardiovascular diseases 2) understand the relationship between these factors and diseases 3) based on the finding develop better strategies to for screening individuals at risk of those diseases.

Related publications

Author(s)
Ming Wai Yeung, Pim van der Harst, Niek Verweij
Journal
STAR Protocols
Author(s)
Ming Wai Yeung, M. Abdullah Said, Yordi J. van de Vegte, Niek Verweij, Robin P.F. Dullaart, Pim van der Harst
Journal
Atherosclerosis Plus
Author(s)
Ming Wai Yeung, Rutger R. van de Leur, Jan Walter Benjamins, Melle B. Vessies, Bram Ruijsink, Esther Puyol-Antón, J. Peter van Tintelen, Niek Verweij,…
Journal
iScience
Author(s)
Wenbo Zhang, Peter J van der Most, Siqi Wang, Zoha Kamali, Alice Giontella, Sofia Enhörning, Ron T Gansevoort, Pim van der Harst, Stephan J…
Journal
EBioMedicine
  • clinical signs and symptoms

All publications