Last updated:
ID:
43252
Start date:
13 February 2019
Project status:
Closed
Principal investigator:
Dr Qi Yan
Lead institution:
Columbia University, United States of America

Asthma is a common and complex disease with substantial heritability. It has been shown that asthma is associated with clinical variables and genetics, but their association to asthma is still not sufficiently characterized. Currently, there is no gold standard for diagnosis of asthma because of its heterogeneity and complexity. Thus, an accurate asthma prediction model is on demand. With the growth of big data in the biomedical community, researchers are able to use a large sample size and large scale of variables to predict disease status with higher accuracy. Thus, in this study, we propose to use deep learning to train a prediction model for asthma diagnosis by using the UK Biobank samples. Our final prediction model will be freely accessible to the research community. This can help asthma to be diagnosed more accurately. We expect that this study takes around 15 months.

Related publications

Author(s)
Ge Yang, Yueh-Ying Han, Erick Forno, Qi Yan, Franziska Rosser, Wei Chen, Juan C Celedón
Journal
The Journal of Allergy and Clinical Immunology In Practice
  • lungs
Author(s)
Yueh-Ying Han, Qi Yan, Ge Yang, Wei Chen, Erick Forno, Juan Carlos Celedon
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Thorax
  • lungs
Author(s)
Alireza Ganjdanesh, Jipeng Zhang, Emily Y Chew, Ying Ding, Heng Huang, Wei Chen
Journal
PNAS Nexus
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Qi Yan, Daniel E. Weeks, Hongyi Xin, Anand Swaroop, Emily Y. Chew, Heng Huang, Ying Ding, Wei Chen
Journal
Nature Machine Intelligence
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Yueh-Ying Han, Qi Yan, Wei Chen, Juan C. Celedón
Journal
European Respiratory Journal
  • lungs
  • mental health
Author(s)
Yueh-Ying Han, Qi Yan, Wei Chen, Erick Forno, Juan C Celedón
Journal
Annals of Allergy Asthma & Immunology
  • lungs

All publications