Principal Investigator: Dr Kathryn McCarthy
Department: General Surgery, North Bristol NHS Trust
North Bristol NHS Trust, General Surgery, Brunel Building, Southmead
Hospital, Southmead Road, Bristol, BS10 5NB
Colon cancer is one of the leading causes of cancer related deaths in the UK.
Similarly non-malignant bowel conditions such as rectal prolapse affect a large
proportion of the population.
We aim to identify common risk factors for bowel disease in order to correlate
known associations to see if they hold true within the UK Biobank population.
In particular, we are interested in lifestyle factors such as obesity, dietary
factors, levels of exercise and type of work. In females, we are particularly
interested in menstrual and obstetric history as a possible precursor to the
development of rectal prolapse.
The initial application will form the basis of an intended long term project
using this resource. We also hope to link any risk factors that we identify to
colon cancers that have already developed in the UK Biobank population. All our data will be published and returned to the UK Biobank for enrichment
of the resource. We do not require participant re-contact or the depletion of