Principal Investigator: Dr Francesco Zaccardi
Institution: University of LeicesterTags: 14146, activity, alcohol, BMI, diet, Multi-morbidity, smoking
Collaborator: Mr Dawit Zemedikun, University of Birmingham, Birmingham, UK
1a: We aim to :
• investigate the prevalence of multi-morbidity (presence of more than two chronic conditions) in a large representative sample of older adults from the UK
• identify patterns of multi-morbidity in the distribution of chronic diseases and age and gender specific differences in these patterns
• assess the association between lifestyle risk factors (physical activity, smoking, alcohol use, Body Mass Index, fruit and vegetable intake) and multi-morbidity
1b: The UK Biobank is aimed at supporting research intended to improve prevention, diagnosis and treatment of illness and promotion of health. This project aligns very closely with the purpose of Biobank and addresses a very important issue in the current health care settings in the UK. A better understanding of multi-morbidity and its associated factors will not only feed into the prevention and care guidelines for multi-morbidity but also aid in defragmentation of care for these patients.
1c: We will quantify the extent to which multi-morbidity affects older adults in the population and common clusters of chronic conditions. We will also then assess the variations in these clusters by age and sex and the association between multi-morbidity and lifestyle factors.
1d: Full cohort
We aim to :
– investigate the prevalence of multimorbidity (presence of more than two chronic conditions) in a large representative sample of older adults from the UK
– identify patterns of multimorbidity in the distribution of chronic diseases and age and gender specific differences in these patterns
– assess the association between lifestyle risk factors (physical activity, smoking, alcohol use, Body Mass Index, fruit and vegetable intake) and multimorbidity
We aim, however, also to compare different statistical methods to obtain the results as we realised (during the analyses) that different methods could give a bit different results. We aim to prepare a separate research manuscript just to explore the impact of different methods on the results but the original biomedical question remains the same (multimorbidity and association with lifestyle factors).
Last updated Sep 16, 2019