Principal Investigator: Dr Jimmy Chun Yu Louie
University of Hong KongTags: 44407, cardiovascular, Coffee, metabolic-syndrome, obesity, single nucleotide polymorphisms, sugar
Coffee is one of the most commonly consumed drinks in the world. While coffee is best known for its effect on improving alertness, the health effects brought about by drinking coffee have also been topics of intense research. Many population-based studies have concluded usual coffee drinkers were less likely to suffer from several lifestyle-related chronic diseases, such as type 2 diabetes (T2DM) and cardiovascular diseases (CVDs).
Metabolic syndrome refers to the condition of having several metabolic disorders at the same time, such as obesity, high glucose level, high blood cholesterol and lipid levels, and high blood pressure. These components of metabolic syndrome are greatly related to T2DM and CVDs, which were found to be protected against by drinking coffee in previous study findings. Hence, coffee drinkers may potentially be less likely to have metabolic syndrome, yet this relationship was seldom studied previously. Therefore, this project aims at investigating this linkage.
The findings from this project will enhance our understanding towards the protective effect of drinking coffee against metabolic syndrome. The effects of some factors regarding the effects of drinking coffee will also be studied, such as the effects of drinking different types of coffee (e.g. espresso, instant, and boiled coffee), the effects of adding of milk and sugar into coffee, and the role played by genetic variations. This project is expected to last for two years.
Project extension – June 2020
The project aims to investigate the association between coffee consumption and metabolic syndrome. Several factors that may affect this association will also be assessed, such as the effects of consuming different types of coffee, the effects of adding milk and sugar into coffee, and the role played by genetic variations.
The association between coffee consumption and the individual abnormalities included in the definition of MetS, including hyperglycaemia, dyslipidemia, central obesity, and hypertension, will also be investigated. The association between coffee consumption and type 2 diabetes, as well as cardiovascular diseases, will also be assessed. Several factors of coffee consumption habit, such as the effects of consuming different types of coffee and the effects of adding milk and sugar into coffee, will be considered when assessing the association. Mendelian randomisation will also be used to assess whether a causal relationship could be established.
Last updated Jun 2, 2020