Principal Investigator: Professor Andrey Rzhetsky
Department: University of ChicagoTags: 36647, complex disease, cross-disease-analysis, disease forecasting, genetics, polygenic risk score, statistical genetics
We are aiming to design a method where all diseases can genetically mapped in a single analysis, as opposed to disease-by-disease mapping. We then perform this mapping and use it to predict patient’s future health from her genetics.
Public health impact of the study
Our study (hopefully) will pave way to discovering how the same genetic variant affects multiple diseases. This, in turn, should increase the quality of disease forecasting from individual-specific genetic data. Our hope is that high-quality forecast of likely future pathologies facing particular individual would allow to design patient-specific preventive measures.