The manifestation of COVID-19 has shown discernible variability worldwide. While some infected individuals show little or no symptoms with quicker recovery, others are more grievously affected and even succumbing to it. Recent studies suggest that variability in the host genetic constitution likely underlines the inter-individual and population specific variabilities in COVID-19 and clinical manifestation worldwide. Our study aim to identify the genetic variants associated with COVID-19. We will be comparing the individuals without history of COVID-19 and individuals with history of COVID-19. These association studies will potentially pave the way for the development of population specific therapeutics that might be more effective in combating COVID-19 than generic drugs and approaches. Understanding the genetic information of COVID-19 patients from diverse ethnicities will also help to zero down on genetic variants and biological pathways that are associated with COVID-19 and hence can help to develop targeted more personalized therapies.
