Last updated:
Author(s):
Jared O'Connell, Kevin Sharp, Nick Shrine, Louise Wain, Ian Hall, Martin Tobin, Jean-Francois Zagury, Olivier Delaneau, Jonathan Marchini
Publish date:
6 June 2016
Journal:
Nature Genetics
PubMed ID:
27270105
DOI:
10.1038/ng.3583

Abstract

Jonathan Marchini and colleagues develop a new method for haplotype phasing, SHAPEIT3, capable of handling large data sets from biobanks containing >100,000 genotyped samples. They find that their method is fast and accurate, with a low switch error rate, and can be scaled to data sets from increasingly larger cohorts.

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Institution:
University of Leicester, Great Britain

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