The global incidence of malignancies affecting the urinary tract and male reproductive organs continues to rise, driven by population aging, environmental carcinogen exposure, and improved diagnostic capabilities. However, current knowledge regarding these diseases remains limited.
To address this gap, the present undertaking aims to employ an integrated approach, leveraging the wealth of genetics, metabolomics, transcriptomics, and comprehensive epidemiological data.Through multidimensional analyses, we aim to discover new risk factors, identify potential biomarkers, and understand the causal relationship between various metabolic risk factors and malignancies of the urinary tract and male reproductive organs.
We will combine multi-omics and epidemiological data to discover novel risk factors and biomarkers and provide definitive evidence for known associations between Metabolic syndrome and Urinary system tumor risk reported by traditional observational studies. Our endeavor will encompass the analysis of multi-omics and epidemiological information, enabling us to unravel new risk factors, identify potential biomarkers, and comprehend the intricate web of causal relationships underpinning various Metabolic syndrome and Malignant tumors of the urinary tract and male reproductive organs. This comprehensive exploration will include conditions such as abdominal obesity, dyslipidemia, hypertension, prostate cancer, testicular cancer, bladder cancer, kidney cancer, ureteral cancer, and more.
