Last updated:
ID:
1188960
Start date:
28 March 2026
Project status:
Current
Principal investigator:
Miss Zengyi CHEN
Lead institution:
University of Nottingham Ningbo Campus, China

Work is a central part of adult life. It shapes daily routines, social contacts and financial security. It may also influence how people think, remember and solve problems as they grow older.
This project uses UK Biobank data to study how employment, everyday lifestyle and health relate to cognitive performance and change across adulthood. We will describe patterns of cognition among participants with different work histories. We will then examine how lifestyle, physical health and mental health are linked to these patterns. We will also include biological information, for example clinical measurements and other biomarkers available in the resource, to see whether they help explain or modify the links between work and cognition. Education, basic demographics and baseline health will be considered to reduce the impact of pre-existing differences.
The study will not focus on a single occupation or disease. It will take a broad view of working lives in the cohort. The findings can highlight which combinations of work conditions, lifestyle profiles and health states are associated with more favourable cognitive function. This evidence can support employers, occupational health practitioners and policy makers who want to design jobs and health promotion strategies that help people stay cognitively healthy while they remain in the workforce and as they age.