Approved Research

Air pollution and incidence of breast cancer: a prospective study in the UK biobank.

Lay summary

Breast cancer is the leading cause of cancer death in females and the incidence is increasing. The incidence and progression of breast cancer are influenced by a combination of genetic and environmental factors, including lifestyle and especially, air pollutants. Ambient air pollution (AAP) is a major risk factor for many diseases, however, evidence is sparse and inconclusive on the association between air pollution and breast cancer. Solid and thorough population researches of this issue are needed. We aimed to assess the association of AAP including (PM2.5, PM10, NO2, SO2, CO and O3) with breast cancer risk and compared the breast cancer risk attributable to AAP and other established risk factors. We plan to conduct these comprehensive analyses by running this project for 3 year (2024-2027). Findings regarding environment factors have a significant public health implication in the prevention of breast cancer, reduce the incidence and mortality of breast cancer, and reduce the medical burden of social funds.