Association between food allergies and single nucleotide polymorphisms
Approved Research ID: 43559
Approval date: September 4th 2020
Previous researches from our group have noticed that food-allergic patients demonstrating different dietary habits compared with the general non-allergic population. In addition, single nucleotide polymorphisms have been associated with some diet habits. There seems to be a direct link between genetic variants and food allergies. The aim of the proposed research is to characterise single nucleotide polymorphisms (SNPs) associated with food allergies via a genome-wide association study. Moreover, the study will aim at identifying additional associations involving dietary habits, BMI, age, gender, and ethnicity as co-variants. We will also determine interactions between genetic factors, the food allergy status, and the co-variants.
The estimated duration of the current project is 12 months. Results from this study will increase our understanding of food allergies and will emphasize the important role of SNPs/biomarkers. We aim to explore the mechanisms to be identified as therapeutic targets and help identify individuals at high risk for food allergy.