Approved Research

Association of malignant tumor with Toxoplasma gondii infection

Lay summary

Toxoplasma gondii (T. gondii) infection is becoming a major cause of morbidity and mortality in immunocompromised patients such as malignant tumor patients. However, the disease burden of T. gondii infection in the malignant tumor patients is poorly understood. Therefore, we will use data obtained from the UK Biobank to evaluate the incidence, treatment, prognosis of malignant tumor patients co-infected with T. gondii, and to predict risk factors associated with the prevalence of T. gondii infection in these populations. We aim to complete this project within one year. The results of this research will contribute to the future scientific researches in this area, and help us understand the situation of T. gondii infection in malignant tumor patients; so as to emphasize the importance of routine surveillance of T. gondii infection in these populations, as well as the information targeting preventive measures and treatment strategies.