Approved Research

Association of serum calcium, vitamin D and C-reactive protein with all-cause and cause-specific mortality in osteoarthritis

Lay summary

Osteoarthritis is the most common musculoskeletal disease and the leading cause of disability globally. Vitamin D deficiency is the most common nutritional deficiency worldwide which can also regulate the serum calcium. In addition, the serum C-reactive protein was also highly associated with osteoarthritis. However, there are few studies investigating the effect of serum calcium, vitamin D and C-reactive protein on the all-cause and cause-specific mortality in osteoarthritis population.

Our project will involve looking at the baseline serum calcium, vitamin D and C-reactive protein and their associations with mortality in the osteoarthritis population. We expect the project duration to be a period of several months. This research will help us to understand more about the role of serum calcium, vitamin D and C-reactive protein in osteoarthritis, in particular, their longitudinal roles in death.