Approved Research

Associations of environmental and genetic factors with the risks of incidence and progression of cardiometabolic diseases

Lay summary

The overall objective of the research is to improve the quality of life for the patients with cardiovascular related diseases.The research includes two parts' data, analysing our own cohort data and UK biobank data. The main purpose of this study is to verify that environmental exposure (lifestyle, diets, psychological factor, economic conditions, etc.), and genetic factors which have significant effects on these disease's development or regression. In addition, the investigators will further study the genetic mechanism of these diseases from the molecular genetic level, and explore the contribution and impact of genetic diversity on the treatment effect. At the same time, explore and establish a cardiovascular related diseases prevention and control system and effective mechanism of hospital.This research will provide theoretical and experimental basis for formulating strategies for large-scale intervention of related diseases, so as to improve the prevention, treatment and prognosis. We strive to reduce the disease and social burden.