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Approved research

Combining brain physiology, polygenic scores, and dietary intake patterns to better understand the causes and consequences of obesity-related diseases.

Principal Investigator: Professor Philipp Koellinger
Approved Research ID: 41060
Approval date: December 6th 2019

Lay summary

We aim to break new grounds in the understanding of the relationship between eating behavior and brain physiology. Our study will combine the available brain images in the UKB with information about dietary intake, related health-outcomes, and genome-wide data. The insights from our research will advance the understanding of the biological mechanisms underlying dietary intake, and may identify targets of novel treatments and interventions for eating disorders and obesity. Importantly, our research design will combine neurophysiological measures with behavioral and genetic data that will allow addressing questions regarding the direction of causal relationships between brain physiology, eating behavior, and health.