Most of the pulmonary diseases may be influenced by race, ethnicity and other genetic factors. However, limited data exist that compare these pulmonary diseases such as COPD, IPF, VTE et al between different ethnic groups, especially in the Chinese population and Western population. Asia is the most populous continent, accounting for 60% of the world population. As the world's most populated country, the Chinese population is accounted for like 1/5 of the world's population. Meanwhile, the evidence shows pulmonary diseases have been the primary diseases affecting Chinese population health. But these patients are always underrepresented in human genetics research. Our research results will add important evidence on the genetic diversity in Chinese patients and UK patients in pulmonary diseases.