Approved Research

Investigating factors that influence Metabolic Syndrome

Lay summary

Original scope:

Metabolic syndrome (MetS) is a condition that includes the presence of a cluster of risk factors (diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure) specific for cardiovascular disease. Previous studies have shown that MetS was likely to be associated with increased risk of cancer but the evidence remain unclear. The aims of this application are:

1.            To investigate the MetS and subsequent overall and site-specific cancer risk/mortality

2.            To investigate individual components of MetS and cancer risk/mortality

3.            To investigate the interaction of individual components of MetS, in relation with cancer risk/mortality

New scope:

The scope of this application are:

1.            To investigate the MetS and subsequent overall and site-specific cancer risk/mortality

2.            To investigate individual components of MetS and cancer risk/mortality

3.            To investigate the interaction of individual components of MetS, in relation with cancer risk/mortality

4.     To investigate the factors that influence MetS (lifestyle factors (diet, physical activity, smoking, alcohol drinking, etc.), medicine use (antihypertensive drugs, antidiabetics medicine, strain, NSAIDs, PPIs, aspirin, etc.), and genetic factors) and health risk other than cancer (including CVD, respiratory diseases, digestive diseases, neurological diseases, endocrine diseases, mortality and etc.)