Approved Research

Investigation the Association between Physical Activity and Sex-specific Cancer Risk Using the UK Biobank Data

Lay summary

Cancer risk is a person's chance of getting cancer. It is affected by many things, like genetics, habits, environmental exposure, and health problems. Sex can also be a big factor, since some kinds of cancer are more common in one sex than the other. For example, women are more likely to get breast cancer, while men are more likely to get prostate cancer. Understanding these differences in cancer risk by gender is important for making targeted plans to avoid cancer and improve health. A lot of study has been done on how physical activity affects the risk of cancer. There is a lot of statistical evidence that shows people who are more active are less likely to get different types of cancer than people who are less active.  But more study is still needed to fully understand and confirm the causal pathways that explain the link between physical activity and a lower risk of cancer. We aim to use data from the UK Biobank to look into the link between physical exercise and cancer risk, focusing on differences between men and women. The UK Biobank is a large-scale study project that collects health-related information from more than half a million people all over the UK. By looking at the data, we wanted to find out more about how exercise affects the risk of cancer for each gender.We hope that this study will add to the growing body of evidence that shows how important physical activity is in preventing cancer. We want to find out more about any possible differences between men and women in cancer risks. This study gives us important information about how each sex's exercise habits affect their chance of getting cancer.