Last updated:
ID:
103736
Start date:
7 September 2023
Project status:
Current
Principal investigator:
Professor Changsheng Ma
Lead institution:
Beijing Anzhen Hospital, Capital Medical University, China

Cardiac arrhythmia and heart failure are major cardiovascular diseases that affect millions of people worldwide. Several metabolic risk factors such as blood pressure and glucose have been implicated in the development and progression of these conditions. Novel imaging phenotypes help achieve accurate risk prediction and effectively identify high-risk patients and risk factors. The study will investigate the relationship between metabolic traits, develop more accurate and personalized approaches for the prevention and treatment of cardiac arrhythmia and heart failure, and identify novel biomarkers and potential drug targets.

Project duration: the project is expected to complete within 3 years. Depending on the progress of the research project, we may extend the scope and/or duration of the project.

Public health impact: Our study will help to understand the relationship between metabolism traits and primary and secondary prevention of cardiac arrythmia and heart failure. Our work will also develop machine learning algorithms based on imaging phenotypes to enable earlier detection and more precise risk stratification.

Related publications

Author(s)
Xiaodong Peng, Yukun Li, Nian Liu, Shijun Xia, Xin Li, Yiwei Lai, Liu He, Caihua Sang, Jianzeng Dong, Changsheng Ma
Journal
Circulation Arrhythmia and Electrophysiology
  • heart and blood vessels
Author(s)
Jiaju Li, Yiwei Lai, Chao Jiang, Mingxiao Li, Zejun Yang, Manlin Zhao, Xiaodong Peng, Sitong Li, Qifan Li, Jiawei Chen, Zhen Wang, Suhui Zhang,…
Journal
European Journal of Preventive Cardiology
Author(s)
Gaifeng Hu, Xiaodong Peng, Liu He, Yiwei Lai, Nian Liu, Xin Li, Caihua Sang, Jianzeng Dong, Changsheng Ma
Journal
ESC Heart Failure
  • heart and blood vessels
Author(s)
Zejun Yang, Yunting Liang, Liu He, Le Zhou, Xiaodong Peng, Yiwei Lai, Cong Yuan, Xiaoxia Liu, Ning Zhou, Weihua Zhang, Caihua Sang, Qian Tong,…
Journal
International Journal of Cardiology Cardiovascular Risk and Prevention
Author(s)
Le Zhou, Zejun Yang, Lan Ren, Gaifeng Hu, Jue Wang, Sitong Li, Xiaodong Peng, Manlin Zhao, Qifan Li, Zixu Zhao, Mingxiao Li, Meiqi Zhao,…
Journal
BMJ Open
  • heart and blood vessels
  • mental health

All publications