Plant foods, nutrients and the risk of morbidity and all-cause and cause-specific mortality: exploring associations with subtypes of plant foods, less common diseases and the underlying mechanisms
Principal Investigator:
Dr Dagfinn Aune
Approved Research ID:
20524
Approval date:
March 12th 2019
Lay summary
We will examine the association between the intakes of fruits, vegetables, grains, legumes, nuts, related nutrients and biomarkers of these foods and the risk of morbidity, all-cause and cause-specific mortality. We wish to conduct a analysis of intake of plant foods, related nutrients and biomarkers in relation to the risk of developing a range of different health conditions to provide a more comprehensive evaluation of the potential benefits of eating more plant foods. We will also examine associations for specific types of plant foods and examine the potential underlying mechanisms that could explain any of the associations that may be observed. The proposed research meets the UK Biobank's aim to improving the knowledge about the role of plant foods in prevention of chronic diseases and mortality We will investigate the association between plant foods, related nutrients (measured using the baseline questionnaire and 24-hour recalls), and biomarkers and: 1) potential biological risk factors (cholesterol, blood glucose, IGF, SHBG, testosterone, oestradiol, blood pressure, C-reactive protein, BMI, waist measures, body fat%) 2) the risk of all-cause and cause-specific mortality. 3) the risk of a wide range of specific disease outcomes