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Approved research

The impact of HLA promiscuity on COVID-19 suceptibility

Principal Investigator: Marcus Daniels
Approved Research ID: 63109
Approval date: June 15th 2020

Lay summary

Although age is a predominant predictor for severe COVID-19 outcomes, people of all ages, even those without other diseases sometimes die. We would like to determine if there is a genetic explanation for all of these severe outcomes. Is it the same pattern and just at an increased frequency with older individuals? As biobanks around the world follow the UK's lead, there is the possibility that governments and hospitals can help to prioritize medical treatment for the most vulnerable. For ethnically diverse countries like the UK, it is also important to understand which forms of virus causing COVID-19 can be vaccinated against in a universal way, versus those that need to be customized to different groups.