Approved Research

The interaction effects of environmental and genetic factors on cardiovascular and mental disorders

Lay summary

Cardiovascular and mental diseases account for a large proportion of the global disease burden. Epidemiological studies have reported a variety of risk factors for cardiovascular and mental diseases. However, the etiology remains unclear. Therefore, we aim to comprehensively examine the potential individual and joint effects of environmental factors, socioeconomic status, lifestyle, and genetic predisposition on cardiovascular and mental diseases. We expect to finish this project during 1.5 to 2 years. The results might provide suitable prediction indicators and prevention strategy to prevent and decrease the occurrence and disease burden of cardiovascular and mental disorders. This is of great public health significance to control cardiovascular and mental diseases, such as ischemic heart disease, stroke, Alzheimer's disease (and other dementias), cardiovascular and mental and so on.