Approved research

To explore the risk factors and related physicochemical and biological characteristics of cardiovascular and cerebrovascular diseases (hypertension, coronary heart disease, stroke, etc.)

Lay summary

Objective  To investigate the association between lifestyle, environmental risk, genetic factors and the morbidity and mortality of cardiovascular and cerebrovascular diseases (hypertension, coronary heart disease, heart failure, stroke, etc.), and to explore the biological and imaging features related to the occurrence and development of diseases.

Background Cardiovascular and cerebrovascular diseases are the leading cause of disease death worldwide. Hypertension is the most common disease worldwide, and it is a major risk factor for a variety of cardiovascular and cerebrovascular diseases such as stroke and coronary heart disease, and affects one-third of adults worldwide. According to the survey, in addition to hypertension, psychological, living habits, genetics, environment and other factors have been fully confirmed to be related to cardiovascular and cerebrovascular diseases. Exploring the independent and combined effects of genetic, lifestyle, and environmental risk factors on cardiovascular and cerebrovascular morbidity and mortality will help assess modifiable risks and adopt strategies to prevent cardiovascular and cerebrovascular disease and reduce mortality.

Project duration: 36 months.

Public health impact: Adopt a variety of research strategies to further clarify the risk factors of Cardiovascular and cerebrovascular diseases in the population, clarify the etiology and pathogenesis of Cardiovascular and cerebrovascular diseases, and help improve the prevention and control of Cardiovascular and cerebrovascular diseases.