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Approved Research

Uncovering the genetic basis of reproductive health and its links to general health

Principal Investigator: Dr Alexander Busch
Approved Research ID: 100261
Approval date: April 6th 2023

Lay summary

Our research project aims to understand the genetic factors that contribute to reproductive health and how these factors are linked to other aspects of health. Reproductive health is an important aspect of overall health and well-being, and is essential for the survival and prosperity of individuals and populations. However, reproductive health can be affected by a variety of factors, including genetics, environmental exposures, and societal influences.

By studying the genetic basis of reproductive health in a large, diverse population, we hope to identify key genetic risk factors for reproductive health disorders, such as infertility and preterm birth. We will also investigate the relationships between these genetic risk factors and other aspects of health, such as cardiovascular health and mental health.

To do this, we will use data from the UK Biobank, which is a large collection of health, lifestyle, and genetic information for a diverse population. We will use a combination of genetic association analyses and machine learning techniques to analyze the data and identify patterns that may be related to reproductive health and its links to other aspects of health.

Our research has the potential to make important contributions to the understanding of the genetic basis of reproductive health and its links to other aspects of health. By identifying key modifiable risk factors for reproductive health disorders, this research could help to reduce the burden of these disorders on individuals and families, and may also have broader benefits for public health.

The project is expected to last for approximately 3 years. We hope that the results of our research will be used to inform the development of targeted treatments and interventions for reproductive health disorders, and may also lead to the discovery of new therapeutic targets for other health conditions.