Aim: To investigate whether herpes-zoster and herpes simplex virus-related diseases are associated with frailty
Scientific rationale: Recent reports showed that herpes zoster and herpes simplex viruses-related diseases were associated with neurodegenerative diseases including Alzheimer’s disease and cardiovascular diseases which are major risk factors of frailty in older adults. Herpes zoster and herpes simplex viruses -related disease are frequent in older adults because those people have decline of immunological function, which enable these viruses reactivate and cause related-diseases in those. However, it remains unknown whether those herpes virus-related diseases are associated with frailty.
Project duration: 2024 to 2029
Public health impact: Preventions of those herpes zoster and herpes simplex virus-related disease with vaccination or rapid prescription of medications against these herpes viruses will contribute to prevention of frailty in middle-age and older adults in case that the study show that those herpes virus-related diseases are associated with frailty in those.
