The main aim of this research is to comprehensively investigate the profound impact of the triple burden of malnutrition (TBM) on the risk of cancer and cardiometabolic diseases (CMDs). Furthermore, the effects of selection bias adjustment for predicting cancer and CMDs risk will be investigated. Accordingly, the research questions and aims are set as follows:
Research Question(s) and Aim(s)
Questions:
* How will the selection bias adjustment affect the prediction of the risk of cancer and CMDs?
* How do the different forms of malnutrition (undernutrition, overnutrition, and micronutrient deficiencies) impact cancer and CMDs?
* What are the mediating effects of the multi-omics (proteomic and metabolomic) factors linking the triple burden of malnutrition with cancer and CMDs?
Aims:
* Assess the effects of selection bias adjustment for the prediction of the risk of cancer and CMDs.
* To compare the impact of different forms of malnutrition on the risk of cancer and CMDs.
* To assess the mediating effects of multi-omics factors linking the TBM with the risk of cancer and CMDs.