Neurological disorders such as Alzheimer’s disease, Parkinson’s disease, and stroke result from complex interactions among genetic, systemic, behavioral, and environmental factors. This project aims to explore how multi-organ imaging phenotypes, multi-omics data (genomics, proteomics, metabolomics, epigenomics), lifestyle behaviors, and environmental exposures contribute to the risk and development of neurological disorders.
We will address the following key questions:
How do brain and peripheral organ structural changes relate to neurological outcomes?
Which circulating biomarkers and molecular profiles are predictive of disease onset?
How do genetic and epigenetic factors interact with modifiable exposures such as air pollution, diet, and physical activity?
Can integrative models combining imaging, omics, and environmental data improve early disease prediction?
This project seeks to develop a systems-level understanding of neurological disorders, with potential applications in risk stratification, biomarker discovery, and targeted prevention strategies.
