aims
Our research aims to explore the influence of multiple omics features (genomics, proteomics, metabolomics, and exposome, etc.) and their intricate interactions on aging and aging-related diseases, providing new perspectives for deciphering biological processes and molecular events. Furthermore, by pinpointing shared signals between molecular phenotypes and disease GWAS, we aim to unveil the black box from genetic variation to the onset of diseases, understanding the underlying biological mechanisms.
scientific rationale
Currently, the global population of elderly people is growing at an unprecedented rate. It is projected that by 2050, the population aged 65 and above will reach 1.6 billion. The continuous increase in incidence of age-driven chronic diseases will place a substantial burden on global socioeconomic frameworks. In this context, the scientific challenge of how to address aging, with the goal of fostering healthy aging, has come into the limelight.
project duration
This project is expected to be completed within 36 months.
public health impact
The results of this research will contribute to a comprehensive understanding of the developmental process of chronic diseases and support precise personal prevention. Concurrently, the findings will provide invaluable evidence for the general public and organizations, enhancing their understanding of public physical and mental health. This will assist in improving lifestyle choices, preventing chronic diseases, and enabling the adoption of early disease prevention interventions.