The association between cigarette smoking and the risk of prostate cancer remains controversial. Cigarette smoking at the time of diagnosis has been linked to increased risks of biochemical recurrence, metastasis, and mortality among patients with prostate cancer. However, post-diagnosis smoking patterns in patients with prostate cancer are rarely reported, and the impact of continued smoking and smoking cessation on the prognosis of prostate cancer remains unclear. We perform this project to investigate the patterns and correlates of cigarette smoking in patients with prostate cancer and examine the association of cigarette smoking patterns after cancer diagnosis with all-cause and cause-specific mortality.