Cardiometabolic diseases are the predominant cause of mortality, morbidity and healthcare spending globally, and are believed to result in part from the combined additive and synergistic effects of genetic and environmental risk factors. Environmental exposures such as diet and physical activity have enormous potential for prevention and treatment of these diseases, but no single therapy works well in all individuals. Therefore, we raise the question whether there are undiscovered risk factors related to cardiovascular metabolic diseases, if there are, whether there is interaction between these risk factors, and whether they are genetically related.
we want to utilize both quantitative and qualitative data to study the biological, physical or imaging measurements, behavioral, environmental, and genetic factors affecting or predicating the incidence of cardiometabolic diseases, and the risk of adverse outcomes in patients with cardiometabolic diseases. At the same time, we will investigate environmental-genetic interactions on cardiometabolic diseases. We also aim to identify new genetic risk loci or study on the previously identified risk sites of cardiac metabolic diseases.
