Research Title:
Associations of physical activity with chronic diseases, cardiorespiratory function, and cognitive function
Research Questions:
What is the relationship between physical activity and the incidence and progression of chronic diseases (e.g., cardiovascular disease, diabetes, osteoarthritis)?
How does physical activity influence cardiorespiratory function and cognitive performance in adults, particularly in aging populations?
Do cardiorespiratory and cognitive functions mediate the relationship between physical activity and chronic disease outcomes?
Objectives:
To examine the association between physical activity levels and the risk of developing or dying from chronic diseases.
To investigate the impact of physical activity on cardiorespiratory fitness and cognitive function.
To assess whether cardiorespiratory and cognitive functions act as mediators in the pathway linking physical activity to chronic disease prevention.
To provide evidence supporting targeted health promotion strategies involving physical activity.
Scientific Rationale:
Chronic diseases are leading contributors to global disability and mortality, especially in aging populations. Physical activity has been shown to influence multiple physiological systems, including cardiovascular and respiratory health, as well as cognitive functioning. However, the complex relationships between these domains remain insufficiently understood. By leveraging large-scale population data, this research will clarify the mechanisms by which physical activity confers protective effects against chronic conditions, ultimately informing preventative strategies and promoting healthy aging.