Understated Cognitive Impairment (UCI) corresponds to a significant deficit in cognitive performance in the absence of subjective cognitive complaints (SCCs). A significant proportion (30%) of 50-65 years old had pathological cognitive performance in the absence of SCCs associated with cardiovascular risk factors, obesity, and metabolic syndrome. These factors and UCI has already been reported to be related to a higher risk of cognitive decline and dementia. However, no study of UCI in this age group has yet used a comprehensive battery of cognitive tests to determine whether domains other than the executive one are impacted. Advanced automated MRI methods have emerged as more objective and precise alternative to assess brain damage related to neurological deficits.
