Last updated:
ID:
358626
Start date:
11 March 2025
Project status:
Current
Principal investigator:
Professor Emilton Lima Junior
Lead institution:
Universidade Federal do Paraná, Brazil

The objective of this research is to understand the relationship between venous disease and cardiovascular events such as stroke, heart attack, and their associated risk factors, including high blood pressure, diabetes, and smoking habits. Increasing evidence indicates a significant connection between these conditions. Substances secreted by cells in the arterial system are similar, if not identical, to those produced by cells in the venous walls. This suggests a potential crosstalk of risk factors throughout the circulatory system, where a chronic inflammatory state in the veins could play a crucial role in severe cardiovascular diseases, including those affecting cardioimmunometabolic health.
At rest, blood takes approximately one minute to travel through the body’s network of arteries and veins, highlighting the ongoing communication between the heart, arteries, and veins in both healthy and diseased states.
The study is expected to last for 36 months. Investigating this relationship is important because venous disease might be a preventable risk factor for cardiovascular events. Understanding this connection could lead to improved prevention and treatment strategies, ultimately reducing the incidence of heart attacks, strokes, and related health issues.