Autoimmune diseases are a group of disorders characterized by an abnormal immune response leading to illness in various organs. There is an unmet need to understand the contribution of genetic changes to these disorders. Our long-term goal is to identify the causes of these disorders and develop personalized treatment approaches. Our study aims include: 1. Understanding the contribution of common and rare genetic variants in autoimmune diseases. 2. Prioritizing putative causal genes mediating the connection between genetic variants and autoimmune diseases. 3. Predicting an individual’s risk of developing autoimmune diseases based on their genetic information. The project duration is three years. This study may help to better understand the causes of autoimmune diseases and facilitate the development of targeted treatments in the future.
