Aims: To investigate whether hypertension or diabetes after standardized treatment, as well as comorbidity of hypertension, diabetes, and sensory dysfunction, have effects on dementia, and mild cognitive impairment.
Scientific rationale: Previous studies have shown that hypertension (HTN), diabetes and sensory dysfunction (SD), such as visual impairment, hearing loss and olfactory dysfunction, are important risk factors for dementia, and MCI. Some studies have explored the association between standardized treatment of HTN and diabetes and cognitive function. Several studies suggested that HTN with diabetes, as well as diabetes with olfactory dysfunction, may impair cognitive function. However, prior studies have yielded conflicting findings regarding the effects of standardized treatment for hypertension and diabetes on cognitive function. Additionally, to our knowledge, the effects of comorbidity of HTN, diabetes, and SDs on dementia, and MCI remain unclear.
Project duration: 36 months.
Public health impact: The findings of this study will support that early screening and active intervention for sensory dysfunction, as well as standardized treatment of hypertension and diabetes, is necessary to reduce the risk of cognitive impairment in elderly patients with hypertension and diabetes.
