Major approaches to
identify the presence of Alzheimers’
Disease ( AD ) are mini-mental state examination(MMSE) and MRI of the brain
currently.
However patients in some area have
difficulties in accessing the expensive MRI facility.
The number of the patients who can access
MRI facility is increasing
year by year. Thus the cost of MRI is also
increasing.
Therefore in order to accommodate the
patients without MRI data and reduce the
NHS cost for MRI scan there is a need to
find a way to diagnose AD at a lower cost
than currently experiencing.
Blood, urine and saliva are the cheap biomarkers
and there are some reports on the correlation
between such biomarkers and the diagnosis of AD.
This project makes best use of the vast
data available in UKBiobank to
identify the key biomarkers for the diagnosis of the
AD and develops a system which can use the information
from the low-cost biomarkers and MMSE score to
diagnose AD.
The project outcome will lower the cost incurred
on NHS system and give patients a faster diagnosis
than currently experiencing.