Cancer treatments, such as chemotherapy and targeted therapies, have significantly improved survival rates for patients, but they have also led to an increased risk of cardiovascular disease (CVD) among survivors. This growing concern underscores the urgent need to better understand how these treatments impact cardiovascular health and to develop strategies to mitigate these risks. Over a project duration of three years, this study aims to assess the effects of different cancer types and anti-cancer therapies on cardiovascular health by examining their influence on cardiac imaging biomarkers and the associated risk of developing CVD. By systematically identifying and modeling critical risk factors, the research seeks to enhance the accuracy of predictive tools for early detection and prevention of cancer-related CVD. Moreover, the study will explore potential intervention targets that could mitigate or reverse cardiovascular complications arising from cancer treatments. The ultimate goal is to develop innovative strategies that improve patient outcomes and quality of life, addressing a significant public health challenge by reducing the cardiovascular burden on cancer survivors.