Last updated:
ID:
531817
Start date:
14 May 2025
Project status:
Current
Principal investigator:
Mr Juntao Ni
Lead institution:
Zhejiang University, China

Environmental factors can cause various complex diseases in the human body. Environmental factors include the natural environment (such as air pollution, etc.), the social environment (such as smoking, drinking, diet, exercise and other lifestyles, socioeconomic status, education, etc.), and the internal environment of the body (such as blood, urine and other test results, medication history, etc.).
For example, blood test indicators such as serum urea and serum vitamin D levels should be checked, as well as urine test results such as urine specific gravity and urine leukocytes to understand whether they are related to health problems such as cancer and cardiovascular disease; the impact of natural environmental factors (such as nitrogen oxides and sulfur dioxide – major air pollutants) on complex diseases should be actively studied; Moreover, promoting healthy lifestyle behaviors, including not smoking, avoiding obesity, regular exercise, and healthy eating patterns, is the basis of current strategies to improve population health.
Therefore, this study aims to use the UK Biobank cohort data to explore the hypothesis that various environmental factors and the interactions between environmental factors may affect complex diseases (such as cancer, hypertension, diabetes, cardiovascular disease, metabolic syndrome, sensorineural hearing loss, death, etc.). In addition to the general population, we also focus on people with specific diseases, such as cancer, hypertension, diabetes, metabolic syndrome, etc., to study whether the various environmental factors these people are exposed to can prevent the occurrence, progression or death of various diseases. Ultimately, this research aims to contribute to the formulation of public health strategies