The aim of the project is to obtain new fundamental knowledge about the genes involved in the control of coronary artery disease and varicose veins of lower extremities. These cardiovascular diseases affect a large number of people worldwide, significantly impact patients’ quality of life and ability to work and impose a high socioeconomic burden. We plan to apply powerful methods of genetic analysis which allow to identify disease-associated genes that carry rare variants changing the protein structure. Project duration will be 36 months. Data obtained within the proposed project would help to identify novel drug targets and aid the development of new therapeutic interventions.
