Aims and scientific rationale:
This research aims to create a way to understand the variation in the brain’s anatomy as it changes due to age and disease. construct and test models that can predict how the brain changes over time, particularly in relation to ageing and neurodegenerative diseases. It will use Using advanced techniques from artificial intelligence and statistics, such as deep-learning and normative modelling (like baby growth charts), we seek to try to understand how various factors — like age, educational background, disease-related changes, and lifestyle differences — affect the brain anatomy and function.
Project duration:
This project is part of a PhD program and is expected to last up to 3 years.
Public health impact:
Understanding how ageing and disease both affect the brain, and especially how they differ, can help improve how we predict future changes and treat disease. By providing more accurate forecasts for how an individual’s brain might change over time, this work may be able to help doctors tailor treatments more effectively. This may lead to better health outcomes and a higher quality of life for patients.