This research project is about finding new ways to better understand how our behaviors and job types can influence our health. It uses a cutting-edge approach called Mendelian Randomization, which helps researchers see if there’s a cause-and-effect relationship between substance abuse or having a creative job and our well-being. Substance abuse is known to harm health also by negatively affecting socioeconomic factors, but with these new methods, scientists can measure exactly how detrimental the impact is. This is important because people with more money often have better access to healthcare, so understanding how health and wealth affect each other can help make public health policies that work for everyone. There’s also a growing interest in how being creative and having a job that lets you use that creativity might make you healthier. This research aims to provide solid evidence on whether creative jobs can actually lead to better health, and how this relationship might vary depending on a person’s mental health. By using these innovative techniques, the project hopes to offer insights that could lead to public health strategies that not only prevent harm but also promote factors that improve our health.