Disease areas:
  • brain
  • heart and blood vessels
  • nutrition and metabolism
Last updated:
Author(s):
Jimmy Z Liu, Yaniv Erlich, Joseph K Pickrell
Publish date:
16 January 2017
Journal:
Nature Genetics
PubMed ID:
28092683
DOI:
10.1038/ng.3766

Abstract

Jimmy Liu and colleagues perform genome-wide association by proxy (GWAX) in a large population cohort by replacing cases with their first-degree relatives. They apply GWAX to 12 common diseases and show its utility by identifying new risk loci for Alzheimer’s disease, coronary artery disease and type 2 diabetes.

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Institution:
Columbia University, United States of America

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