Abstract
We collated GWAS data from multiple traits measured accross several diverse cohortse cohorts: UK Biobank, FINRISK, Chinese NIPT, Biobank Japan, APCDR and PAGE. We evaluated how robust signals of polygenic adaptation are to the choice of GWAS cohort used to identify associated variants and their effect size estimates. We show that meta analysis creates overdispersion across populations which appears likes signs of polygenetic seleciton.