Disease areas:
  • heart and blood vessels
Last updated:
Author(s):
Ruben N Eppinga, Yanick Hagemeijer, Stephen Burgess, David A Hinds, Kari Stefansson, Daniel F Gudbjartsson, Dirk J van Veldhuisen, Patricia B Munroe, Niek Verweij, Pim van der Harst
Publish date:
31 October 2016
Journal:
Nature Genetics
PubMed ID:
27798624
DOI:
10.1038/ng.3708

Abstract

Pim van der Harst and colleagues report a genome-wide association study for resting heart rate in individuals of European ancestry and identify 64 associated loci, 46 of which have not been previously reported. A genetic risk score constructed using the associated variants is significantly associated with increased mortality risk.

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Institution:
University Medical Center Groningen, Netherlands

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