Find out what your UK Biobank analysis could cost.

“I was surprised by how low compute costs were for my project. I did my whole analysis for under £5.”

Dr Dylan Williams, University College London, UK

The UK Biobank Research Analysis Platform (UKB-RAP) provides unmatched access to UK Biobank’s vast database within a restricted, consistent and sophisticated research environment.  With over 30 petabytes of individual-level data stored centrally, the UKB-RAP minimises the risks and costs associated with local storage or data transfer. 

With a range of financial support available in credits towards the cost of analyses, many researchers can conduct their analysis with little to no cost at all.  

When you run analyses on UKB-RAP, you can choose how your compute is set up. Use this tool to see how different configurations change the cost profile for your analysis.  

New to cloud computing?

This tool uses terms like spot and on-demand instances. In most cases, we recommend you use spot instances to save on costs.

Find detailed guidance on understanding cloud computing, virtual machines and instances and balancing speed and cost on UKB-RAP on our researcher Community, a hub for knowledge, collaboration and learning.

More about costs

Access to UK Biobank data involves a fee. The costs shown in this calculator relate to using UKB-RAP only and not the initial access fee.

You could be eligible for free financial support, including reduced access fees or £1,000 in credits to support with costs in the platform. Explore our financial support to see what support is available to you.

Get started with your estimate

Compute

The processing power and memory required for your analysis

Choose from a selection of pre-built instance types based on typical projects, or build your own custom instance.

Added to project:

  • Nothing added yet

Next steps

Add a compute instance

Pre-built instance types

Low compute + low memory

Suitable for small datasets and simple analyses.

  • 2 vCPU, 4 GiB RAM, 50 GiB Storage

    mem1_ssd1_v2_x2

    A lightweight option for testing workflows or analysing small amounts of data

    Spot
    £0.0168 per hour
    On-demand
    £0.0628 per hour
  • 2 vCPU, 4 GiB RAM, 159 GiB Storage

    mem1_ssd2_v2_x2

    Lightweight processing power, but with more storage via Amazon EBS, for workflows that need to keep more data

    Spot
    £0.0424 per hour
    On-demand
    £0.0808 per hour
  • 2 vCPU, 8 GiB RAM, 75 GiB Storage

    mem2_ssd1_v2_x2

    General purpose option with extra memory via SSD, for balanced compute and memory workloads

    Spot
    £0.0168 per hour
    On-demand
    £0.0716 per hour
  • 2 vCPU, 8 GiB RAM, 160 GiB Storage

    mem2_ssd2_v2_x2

    General purpose option with flexible storage via Amazon EBS, for workflows that need to keep more data

    Spot
    £0.0424 per hour
    On-demand
    £0.089 per hour
  • 2 vCPU, 16 GiB RAM, 75 GiB Storage

    mem3_ssd1_v2_x2

    Extra memory via SSD, for analyses that need to hold more data in memory while processing

    Spot
    £0.0168 per hour
    On-demand
    £0.0922 per hour
Low compute + high memory

Suitable for moderate datasets and standard analyses.

  • 2 vCPU, 8 GiB RAM, 1000 GiB Storage

    mem2_hdd2_v2_x2

    Modest processing power with very large storage via HDD, suitable for storing and processing large datasets

    Spot
    £0.0898 per hour
    On-demand
    £0.1336 per hour
  • 2 vCPU, 16 GiB RAM, 500 GiB Storage

    mem3_hdd2_v2_x2

    High memory and large storage via HDD, for workflows that deal with sizeable datasets

    Spot
    £0.0532 per hour
    On-demand
    £0.1172 per hour
  • 2 vCPU, 15.25 GiB RAM, 475 GiB Storage

    mem3_ssd2_v2_x2

    Large storage via SSD for I/O intensive applications. Designed for tasks that frequently read and write large amounts of data to disk

    Spot
    £0.0988 per hour
    On-demand
    £0.0988 per hour
  • 2 vCPU, 16 GiB RAM, 1250 GiB Storage

    mem3_ssd3_x2

    Very large storage capacity via NVMe for data-heavy projects requiring low-latency transactional I/O and large datasets

    Spot
    £0.1348 per hour
    On-demand
    £0.1436 per hour
High compute + low memory

Suitable for intensive computations on moderate datasets.

  • 4 vCPU, 8 GiB RAM, 100 GiB Storage

    mem1_ssd1_v2_x4

    More processing power for data analysis, preprocessing, and routine compute tasks

    Spot
    £0.0336 per hour
    On-demand
    £0.1256 per hour
  • 8 vCPU, 16 GiB RAM, 200 GiB Storage

    mem1_ssd1_v2_x8

    Balanced compute capacity for moderate data processing and parallel computing tasks

    Spot
    £0.0672 per hour
    On-demand
    £0.2512 per hour
  • 4 vCPU, 16 GiB RAM, 150 GiB Storage

    mem2_ssd1_v2_x4

    A flexible option with balanced compute and memory for databases, web servers, and general applications

    Spot
    £0.0336 per hour
    On-demand
    £0.1432 per hour
  • 32 vCPU, 128 GiB RAM, 900 GiB Storage (1 GPU)

    mem2_ssd1_gpu1_x32

    High-performance option with a GPU, often used for machine learning, image analysis, and other intensive computing tasks

    Spot
    £1.2192 per hour
    On-demand
    £1.3888 per hour
High compute + high memory

Suitable for large datasets and complex analyses.

  • 16 vCPU, 32 GiB RAM, 400 GiB Storage

    mem1_ssd1_v2_x16

    High-performance option for demanding analyses and multi-threaded workloads

    Spot
    £0.1344 per hour
    On-demand
    £0.5024 per hour
  • 36 vCPU, 72 GiB RAM, 900 GiB Storage

    mem1_ssd1_v2_x36

    Large-scale compute demanding parallel processing and bioinformatics pipelines

    Spot
    £0.3024 per hour
    On-demand
    £1.1304 per hour
  • 72 vCPU, 144 GiB RAM, 1800 GiB Storage

    mem1_ssd1_v2_x72

    Maximum compute capacity for large-scale parallel computing and genomic analysis

    Spot
    £0.6048 per hour
    On-demand
    £2.2608 per hour
  • 4 vCPU, 8 GiB RAM, 318 GiB Storage

    mem1_ssd2_v2_x4

    Moderate compute with larger storage via EBS for data-intensive analyses that need flexible storage

    Spot
    £0.0848 per hour
    On-demand
    £0.1616 per hour
  • 8 vCPU, 16 GiB RAM, 639 GiB Storage

    mem1_ssd2_v2_x8

    Higher compute power with substantial storage via EBS for data-intensive analyses

    Spot
    £0.1696 per hour
    On-demand
    £0.3232 per hour
  • 2 vCPU, 4 GiB RAM, 200 GiB Storage

    mem1_hdd1_v2_x2

    A lower-cost option with moderate storage via HDD, for data-intensive batch processing

    Spot
    £0.0314 per hour
    On-demand
    £0.0796 per hour
Machine learning

Suitable for machine learning and deep learning tasks.

  • 16 vCPU, 64 GiB RAM, 225 GiB Storage (1 GPU)

    mem2_ssd1_gpu_x16

    Mid-range GPU option for training smaller models and running ML workflows

    Spot
    £0.6432 per hour
    On-demand
    £0.7696 per hour
  • 64 vCPU, 256 GiB RAM, 900 GiB Storage (1 GPU)

    mem2_ssd1_gpu1_x64

    High-performance GPU setup for intensive ML training and rendering tasks

    Spot
    £2.4384 per hour
    On-demand
    £2.7776 per hour
  • 48 vCPU, 192 GiB RAM, 900 GiB Storage (4 GPUs)

    mem2_ssd1_gpu4_x48

    Multiple GPUs for faster training of large models and parallel ML tasks

    Spot
    £2.1936 per hour
    On-demand
    £2.5008 per hour
  • 4 vCPU, 16 GiB RAM, 250 GiB Storage (1 GPU)

    mem2_ssd2_gpu1_x4

    Latest generation GPU instance for ML inference and graphics rendering

    Spot
    £0.6116 per hour
    On-demand
    £0.6968 per hour
  • 8 vCPU, 32 GiB RAM, 450 GiB Storage (1 GPU)

    mem2_ssd2_gpu1_x8

    Small GPU setup for routine ML and image or video processing

    Spot
    £0.72 per hour
    On-demand
    £0.84 per hour
  • 16 vCPU, 64 GiB RAM, 600 GiB Storage (1 GPU)

    mem2_ssd2_gpu1_x16

    High-performance GPU option for AI model training or 3D rendering

    Spot
    £1.0112 per hour
    On-demand
    £1.1248 per hour
  • 32 vCPU, 128 GiB RAM, 900 GiB Storage (1 GPU)

    mem2_ssd2_gpu1_x32

    Large GPU option for complex deep learning and computer vision tasks

    Spot
    £1.488 per hour
    On-demand
    £1.696 per hour
  • 64 vCPU, 256 GiB RAM, 1900 GiB Storage (1 GPU)

    mem2_ssd2_gpu1_x64

    Very large GPU setup for intensive AI training and graphics workloads

    Spot
    £2.8416 per hour
    On-demand
    £2.8416 per hour
  • 48 vCPU, 192 GiB RAM, 3840 GiB Storage (4 GPUs)

    mem2_ssd2_gpu4_x48

    Multi-GPU option with very large storage for large-scale training and data-intensive projects

    Spot
    £3.9312 per hour
    On-demand
    £3.9312 per hour
  • 96 vCPU, 384 GiB RAM, 3800 GiB Storage (4 GPUs)

    mem2_ssd2_gpu4_x96

    Powerful multi-GPU option for training and running ML models at enterprise scale

    Spot
    £5.6448 per hour
    On-demand
    £5.6448 per hour
  • 192 vCPU, 768 GiB RAM, 7600 GiB Storage (8 GPUs)

    mem2_ssd2_gpu8_x192

    Maximum-scale option for very large models and distributed training across multiple GPUs

    Spot
    £11.2896 per hour
    On-demand
    £11.2896 per hour
  • 8 vCPU, 61 GiB RAM, 160 GiB Storage (1 GPU)

    mem3_ssd1_gpu_x8

    GPU option for deep learning training and complex neural network models

    Spot
    £1.9696 per hour
    On-demand
    £1.984 per hour
  • 32 vCPU, 244 GiB RAM, 640 GiB Storage (4 GPUs)

    mem3_ssd1_gpu_x32

    A multi-GPU option for large-scale AI training and demanding compute tasks

    Spot
    £7.8784 per hour
    On-demand
    £7.936 per hour
  • 64 vCPU, 488 GiB RAM, 1280 GiB Storage (8 GPUs)

    mem3_ssd1_gpu_x64

    Our most powerful GPU option for advanced AI research and large distributed workloads

    Spot
    £15.7568 per hour
    On-demand
    £15.872 per hour

Custom instance type

Build a custom configuration

Description

Virtual CPU cores (vCPUs)

Select the number of vCPUs for your custom instance.

RAM (GiB)

Select the amount of RAM (in GiB) for your custom instance.

Storage (GiB)

Select the storage capacity (in GiB) for your custom instance.

GPUs

Select the number of GPUs for your custom instance.

Storage

The amount of space required to hold your uploaded data

Note:

  • We only charge for storage of your own uploaded data. UK Biobank data is stored free of charge.
  • Storage is billed incrementally as your data accumulates; you are not charged the full estimated amount upfront. Try to take this into account when building your estimate.

Added to project:

  • Nothing added yet

Next steps

Add storage

Rate: £0.01783/GB per month

Data transfer

Costs for moving your derived data out of the platform

Note: Transfer fees only apply to data transferred out of the platform. There are no fees for inbound transfer.

Added to project:

  • Nothing added yet

Next steps

Add data transfer

Rate: £0.05015/GB

Total costs

The total estimated costs for your project

Project requirements

  • Nothing added to your project requirements

    Use the sections above to add compute, storage, and data transfer

Estimated total

Spot:
£0.00
On-Demand:
£0.00

All researchers receive £40 of credit when joining UKB-RAP to contribute to compute and storage costs. You may also be eligible for an additional £1,000 in funding support.

We’ll remember your project on this device for 7 days. You can also export your project details as a PDF to share with colleagues or save for later.

Hear from other researchers

Dylan’s project used UK Biobank data to explore the connection between a specific gene variation and risk of Alzheimer’s. 

Dr Dylan Williams headshot

I was surprised by how low compute costs were for my project. I did my whole analysis for under £5.

Brian’s project built a pipeline for filtering, phasing and indexing whole-genome sequencing data for the entire UK Biobank cohort.

Brian Browning headshot

Our project was computation intensive, so we explored ways to save on costs by using spot instances when possible, and selecting the lowest cost compute that was necessary to accomplish a task.

In the end the whole process, including testing, statistical phasing and QC filtering, cost about £14,000.

Join us for a webinar providing you with a clear and practical overview of cloud computing costs within UK Biobank.

Disclaimer

The costs generated by this calculator are estimates only and are provided for general guidance. They do not constitute a formal quote, offer, or guarantee of pricing. Actual costs may vary based on a number of factors including instance usage (added computational time, time taken to spin up/down instances), pro-rataed storage periods, and other variations from the inputted values. Pricing is subject to change at any time. UK Biobank does not provide any warranty (express or implied) regarding the accuracy, completeness, or reliability of the cost estimates generated. UK Biobank accepts no liability for any reliance placed on these estimates or for any loss or damage arising from their use.